What are some of the effects of Natural products and substances, such as Panax ginseng, on tau pathology in Alzheimer’s Disease patients?

Public project summary

Our project involves experiments to see if Panax Ginseng has a correlation to tau proteins in Alzheimer's Disease patients. Alzheimer’s is a disease affecting more than 3 million people in the United States. While we know it's a neurodegenerative disease, the root cause is still debated. Out of the three most prominent hypotheses, the Tau Hypothesis has recently become more salient in regards to Alzheimer’s Disease (AD) patients. Recently, there have been studies that show many neurological benefits from Panax Ginseng- such as maintaining homeostasis, anti-inflammatory, anti-oxidant, anti-apoptotic, and immunostimulatory activities. Examining the molecular interactions between Panax ginseng and tau tangles could provide further evidence of a potential treatment for AD patients.