Volume 1 · Attributed research edition · Brain and cognition

The Effect of Periodontitis on Dementia and Cognitive Impairment: A Meta-Analysis

Haiying Guo; Shuli Chang; Xiaoqin Pi; Fang Hua; Han Jiang; Chang Liu; Minquan Du

International Journal of Environmental Research and Public Health · 2021-06-25 · Meta-analysis

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Original sourceInternational Journal of Environmental Research and Public Health

Multidisciplinary Digital Publishing Institute (MDPI) · Version of record, publisher-supplied full-text XML archived in Europe PMC; correction notices linked where present.

DOI: 10.3390/ijerph18136823

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Interpretation limits

Pooling observational associations does not resolve confounding, reverse causation, heterogeneity in diagnoses or differences in oral-health ascertainment. The synthesis does not establish a single bacterial cause of Alzheimer disease or show that periodontal treatment prevents cognitive decline.

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No retraction or correction notice found in the checked sources. Publisher-supplied full-text XML (article title/type and related notices), Europe PMC core publication types, and publisher-deposited Crossref update-to/updated-by/relation metadata checked on 2026-10-22. Bounded record checks are not a comprehensive guarantee of article integrity; Crossref and repository metadata may be incomplete or lag publisher updates.

Verification date: 2026-10-22

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