Volume 1 · Attributed research edition · Salivary diagnostics

Variability of salivary analytes under daily conditions and their implications for periodontitis biomarkers

Amanda Carolina Souza Delfino Rocha; Renata Klemp Orlandini; Ana Carolina Fragoso Motta; Juliana Barchelli Pinheiro; Gilberto André e Silva; Viviane de Cássia Oliveira; Alan Grupioni Lourenço

Frontiers in Dental Medicine · 2024-03-18 · Repeated-measures biomarker study

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Original sourceFrontiers in Dental Medicine

Frontiers Media SA · Version of record, publisher-supplied full-text XML archived in Europe PMC; correction notices linked where present.

DOI: 10.3389/fdmed.2024.1369186

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License & editionCC BY 4.0

© 2024 Rocha, Orlandini, Motta, Pinheiro, Silva, Oliveira and Lourenço.

https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Interpretation limits

Seventy-nine participants and selected analytes do not establish general reliability for all saliva tests or populations. Collection conditions and assay methods matter. Association with periodontal activity does not establish prediction of cancer, cardiovascular events or dementia.

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No retraction or correction notice found in the checked sources. Publisher-supplied full-text XML (article title/type and related notices), Europe PMC core publication types, and publisher-deposited Crossref update-to/updated-by/relation metadata checked on 2026-10-22. Bounded record checks are not a comprehensive guarantee of article integrity; Crossref and repository metadata may be incomplete or lag publisher updates.

Verification date: 2026-10-22

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