The effect of periodontal treatments on endothelial function in degrees of periodontitis patients: A systematic review and meta-analysis

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DOI: 10.1371/journal.pone.0308793

© 2024 Lyu et al

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Endothelial function is a surrogate outcome; changes do not establish prevention of myocardial infarction or stroke. Treatment heterogeneity, study quality, follow-up and differing baseline periodontal severity constrain generalization. Clinical cardiovascular prevention should continue independently. The abstract labels a six-month result significant despite reporting P=0.09 and a confidence interval crossing zero; readers should use the reported interval and P value and treat that wording as inconsistent.

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Verification date: 2026-10-22

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