Porphyromonas gingivalis and Alzheimer disease: Recent findings and potential therapies

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DOI: 10.1002/jper.20-0104

© 2020 The Authors. Journal of Periodontology published by Wiley Periodicals LLC on behalf of American Academy of Periodontology

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

This 2020 review predates the completed GAIN trial and must not be used as a current efficacy assessment of gingipain inhibition. Mechanistic, post-mortem and animal findings are hypothesis-generating; they do not establish a treatable bacterial cause of Alzheimer disease in humans.

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Verification date: 2026-10-22

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