What kind of peptide chain inhibitor can be created to suppress the FOXP3 transcription factor and impair the development of regulatory T cells?

Public project summary

FOXP3, a protein that takes part in the development of regulatory T cells, is vital for the immune system in recognizing foreign from self cells. However, cancer as well as some autoimmune diseases take advantage of this to hide carcinogenic cells. Consequently, the aim of this research project is to work towards developing improvements for existing inhibitors for FOXP3.